Applications

• V. Piccoli, A. Pádua, L. Martínez, From Hydrogen Bonding to Hydrophobic Control: The Shifting Solvation Mechanism of Ibuprofen in Deep Eutectic Solvents J. Phys. Chem. B, 130 (29): 7388–7400, 2026. [Full Text]

• E. D. S. Mourão, F. C. Ramos, L. Martínez, Molecular Basis for Solvation Structure and Thermodynamics of Polyacrylamide in Aqueous Solutions of Glucose. Macromolecules, 59 (5): 3212–3225, 2026. [Full Text]

• C. A. Tavares, M. Soñora, S. Pantano, L. Martínez, Lipid Architecture in the Zika Virus. ACS Phys. Chem. Au, 6 (4): 665–677, 2026. [Full Text]

• G. C. de Andrade, A. F. Pereira, P. H. B. Ferreira, K. D. da Cruz, G. S. de Sousa, M. F. Mota, R. J. de Oliveira, L. Martínez, M. A. Marques, J. L. Silva, G. A. P. de Oliveira, Cancer-linked aggregation of p53 is driven by sequence-encoded frustration, solvation, and hydrophobic gating absent in its paralogs. Communications Chemistry 2026.

• V. Piccoli, A. F. Pereira, L. Rivillas-Acevedo, N. Pastor, A. E. Peláez-Aguilar, L. Martínez, Preferential Solvation by Trifluoroethanol Drives α-Helical Folding in the Disordered S2 Region of the Escargot Protein. ChemPhysChem, (27) 3, e202500668, 2026. [Full Text]

• A. F. Pereira, L. Martínez, Osmolyte Structural and Thermodynamic Effects Across the Protein Folding Landscape, JACS Au, 5, 12, 6025–6041, 2025. [Full Text].

• V. Piccoli, L. Martínez, Cation Hydrophobicity Effects on Protein Solvation in Aqueous Ionic Liquids, J. Phys. Chem. B, 129 (27) 6765-6776, 2025. [Full Text].

• F. C. Ramos, L. Martínez, Molecular dynamics and solvation structures of the β-glucosidase from Humicola insolens (BGHI) in aqueous solutions containing glucose Int. J. Biol. Macromol. 286 (138210) 2025. [Full Text]

• V. Piccoli, L. Martínez, Competitive Effects of Anions on Protein Solvation by Aqueous Ionic Liquids. J. Phys. Chem. B 128, 7792-7802, 2024. [Full Text]

• A. F. Pereira, L. Martínez, Helical Content Correlations and Hydration Structures of the Folding Ensemble of the B Domain of Protein A. J. Chem. Inf. Model. 64, 3350-3359, 2024. [Full Text]

• A. F. Pereira, V. Piccoli, L. Martínez, Trifluoroethanol direct interactions with protein backbones destabilize alpha-helices. J. Mol. Liq. 365, 120209, 2022. [Full Text]

• V. Piccoli, L. Martínez, Ionic liquid solvation of proteins in native and denatured states. J. Mol. Liq. 363, 119953, 2022. [Full Text]

• V. Piccoli, L. Martínez, Correlated counterion effects in the solvation of proteins by ionic-liquids. J. Mol. Liq. 320, 114347, 2020. [Full Text]

• I. P. de Oliveira, L. Martínez, The shift in urea orientation at protein surfaces at low pH is compatible with a direct mechanism of protein denaturation. Phys. Chem. Chem. Phys. 22, 354-367, 2020. [Full Text]

• I. P. de Oliveira, L. Martínez, Molecular basis for competitive solvation of the Burkholderia cepacia lipase by sorbitol and urea. Phys. Chem. Chem. Phys. 18, 21797-21808, 2016. [Full Text]